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Related Experiment Videos

Completion pneumonectomy for lung metastases.

W Jungraithmayr1, J Hasse, E Stoelben

  • 1Department of Thoracic Surgery, University Hospital of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany. jungrait@chir.ukl.uni-freiburg.de

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|November 4, 2004
PubMed
Summary

Completion pneumonectomy (CP) for lung metastases is controversial. While this study found no perioperative morbidity or mortality, long-term survival remains limited by recurrent metastatic disease.

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Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonary Medicine

Background:

  • Completion pneumonectomy (CP) is accepted for malignant disease but debated for lung metastases due to high perioperative risks and poor prognosis.
  • Limited data exists on the outcomes of CP specifically for lung metastases.

Purpose of the Study:

  • To analyze the postoperative outcomes and long-term results of patients undergoing completion pneumonectomy for lung metastases.

Main Methods:

  • A retrospective review of nine patients who underwent completion pneumonectomy for lung metastases between 1986 and 2003.
  • Analysis of prior metastasectomy procedures, time intervals between surgeries, and perioperative outcomes.
  • Evaluation of long-term survival, recurrence-free survival, and causes of mortality.

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Main Results:

  • Nine patients underwent CP for lung metastases, representing 10% of all CPs and 1.7% of all pneumonectomies.
  • No operative morbidity or mortality was observed.
  • Actual survival was 33%, recurrence-free survival was 11%, and 3-year survival was 34%. One patient remained recurrence-free at 9 months.

Conclusions:

  • CP for lung metastases may be justified given the absence of perioperative complications in this series.
  • Long-term survival is constrained by the potential for contralateral or extrapulmonary metastatic disease.
  • While multiple metastasectomies positively influence survival, CP as the final resection step did not appear to improve long-term survival outcomes.