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Published on: October 14, 2021
A young onset Parkinson's patient: a case study
1Puget Sound Neurology, Tacoma, WA, USA. sjung@harbornet.com
Insights
Young onset Parkinson's disease (YOPD) can cause severe motor complications. Deep brain stimulation significantly improved symptoms and reduced complications in a YOPD patient with a rare complication.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Young onset Parkinson's disease (YOPD), affecting individuals aged 21-40, presents unique challenges with earlier motor complications.
- Approximately 5% of Parkinson's patients are diagnosed with YOPD, experiencing significant morbidity due to disease progression.
Observation:
- This case study details a YOPD patient experiencing severe motor complications, including rhabdomyolysis secondary to dyskinesias—a rare occurrence.
- The patient presented with unusually severe motor symptoms impacting daily function and employment.
Findings:
- Bilateral subthalamic nucleus deep brain stimulation (DBS) was performed to manage the patient's severe YOPD symptoms.
- Post-DBS, the patient demonstrated dramatic improvement in Parkinson's symptoms and significant amelioration of motor complications.
Implications:
- Deep brain stimulation offers a viable and effective treatment for managing severe motor complications in young onset Parkinson's disease.
- Effective patient education and support are crucial for managing YOPD and influencing treatment outcomes.
Abstract:
Young onset Parkinson's disease (YOPD) is defined as idiopathic Parkinson's disease (IPPD) occurring in people between 21 and 40 years of age; it strikes approximately 5% of Parkinson's patients. YOPD has earlier onset of motor complications than later onset Parkinson's disease. Motor complications and disease progression are responsible for devastating morbidity. Current medical and surgical treatments can dramatically ameliorate motor complications and help maintain function and employment. Patient education, support, and advocacy provided by nursing staff can influence the treatment options for these patients, having a significant effect on the future course of the disease. This case history documents the course of a YOPD patient with unusually severe motor complications. He is the only patient at Puget Sound Neurology ever to develop rhabdomyolysis due to dyskinesias. Following bilateral subthalamic nucleus deep brain stimulation, his Parkinson's symptoms have improved dramatically, and his motor complications are significantly improved.
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