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Novel sesterterpenes from Leucosceptrum canum of nepalese origin
Muhammad Iqbal Choudhary1, Rosa Ranjit, Atta-ur-Rahman
1H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi 75270, Pakistan.
Organic Letters
|November 5, 2004
Abstract:
Two novel sesterterpenoids, leucosesterterpenone (1) and leucosesterlactone (2), with novel skeleta were isolated from the hexane extract of the medicinal plant, Leucosceptrum canum. Their structures were established by the analysis of NMR data and the single-crystal X-ray diffraction of compound 1. Compounds 1 and 2 were found to exhibit activity against prolylendopeptidase (PEP).
