Related Experiment Video
Updated: Jun 30, 2026

A Method of Nodose Ganglia Injection in Sprague-Dawley Rat
Published on: November 25, 2014
A modified needle-inside-needle technique for the ganglion impar block
Muhammad A Munir1, Junming Zhang, Mahmood Ahmad
1Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts, USA. mmunir@partners.org
A novel needle-inside-needle technique for ganglion impar blocks may reduce discomfort and risks associated with traditional methods. This approach offers a potentially safer and more effective option for managing pain at the sacrococcygeal junction.
Area of Science:
- Pain Medicine
- Interventional Radiology
- Anesthesiology
Background:
- The ganglion impar, located at the sacrococcygeal junction, is a target for pain management.
- Previous approaches include bent/curved needles via the anococcygeal ligament and straight needles via the sacrococcygeal disc.
Purpose of the Study:
- To describe a novel needle-inside-needle modification for accessing the ganglion impar via the sacrococcygeal disc.
Main Methods:
- A 22-gauge needle was inserted through the sacrococcygeal ligament under fluoroscopy.
- A 25-gauge needle was then introduced through the 22-gauge needle.
- Placement was confirmed using contrast injection (iopamidol 300) and the 'comma sign'.
Main Results:
- The needle-inside-needle technique aims to mitigate risks associated with other approaches.
- Potential benefits include reduced discomfort, tissue trauma, and risk of rectal perforation compared to bent/curved needles.
- It may also reduce risks of discitis and needle breakage associated with longer straight needles.
Conclusions:
- The needle-inside-needle technique offers a promising modification for ganglion impar blockade.
- This technique may improve safety and efficacy in managing sacrococcygeal pain.
- Further studies may be warranted to validate its clinical utility.
More Related Videos
Related Concept Videos
Drugs Acting on Autonomic Ganglia: Blockers
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...

