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Updated: Aug 21, 2026

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons
Published on: September 15, 2014
Lack of association between two polymorphisms of brain-derived neurotrophic factor and response to typical
1Department of Psychiatry, Tampere University Hospital, University of Tampere, Medical School, Tampere, Finland. samia@koti.soon.fi
Abstract:
Several studies have connected brain-derived neurotrophic factor (BDNF) with treatment response to neuroleptics. In recent studies, the BDNF expression was reduced by typical neuroleptics. We conducted a retrospective study on 94 patients with schizophrenia and 98 controls. The BDNF G196A and C270T polymorphisms are not associated with treatment response to typical neuroleptics or with age at first hospitalization. Moreover, these polymorphisms of the BDNF gene are not associated with the risk of schizophrenia.
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