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Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery

K M Paulsson1

  • 1Rayne Institute, Centre for Molecular Medicine, Department of Medicine, University College of London, 5 University street, WC1E 6JJ, London, United Kingdom. k.paulsson@ucl.ac.uk

Cellular and Molecular Life Sciences : CMLS
|November 5, 2004
PubMed
Summary

Major histocompatibility complex (MHC) class I molecules present peptides to CD8+ T cells. This review explores the antigen-processing machinery (APM) and MHC class I, aiding immune system origin understanding.

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