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Updated: Aug 21, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
[Physical activity and dyslipoproteinemia]
D König1, P Deibert, H H Dickhuth
1Universitätsklinikum Freiburg, Med. Klinik, Abt. Prävention, Rehabilitation und Sportmedizin. Koenig@msm1.ukl.uni-freiburg.de
Abstract:
The positive influence of regular physical activity on lipoprotein metabolism and, hence, on the risks for atherogenesis has been documented in controlled studies. Although the levels of total and LDL cholesterol (LDL) usually change only slightly through physical activity, there is a clear change in the LDL composition with a reduction in the atherogenic small dense LDL particle. An activity-induced increase for HDL cholesterol (HDL) between 4 and 29% and a reduction in the triglyceride (TG) level between 4 and 37% are described. To achieve this, it is necessary to increase energy consumption by 1000-1200 kcal/week and to attain an energy consumption of ca. 2500 (> 2000) kcal/week, optimum ca. 3500 kcal/week.
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