Related Experiment Videos
Urinary excretion of vitamin A in critically ill patients complicated with acute renal failure
Vladimir Gavrilov1, Natan Weksler, Ahmed Ahmed
1Pediatric Pharmacology Laboratory, Soroka Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. vladimirgav@hotmail.com
Objective:
Study the possible excretion of vitamin A in urine of critically ill patients complicated with acute renal failure.
Patients And Methods:
Nine Intensive Care Unit patients, age 71.2 +/- 15.7 (mean +/- SD) with acute renal failure were studied. Urinary retinol, creatinine, protein, albumin, and serum creatinine were measured.
Results:
All patients excreted retinol in urine; individual values ranged from 0.007 to 0.379 micromol retinol/mmol creatinine. There was no correlation of urinary retinol/creatinine ratio with serum creatinine or with urinary protein/creatinine and albumin/creatinine ratios.
Conclusion:
Excretion of retinol in urine may be indicative of acute renal failure in critically ill patients.
Related Concept Videos
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury V: Interprofessional Care
Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Acute Kidney Injury VI: Nursing Management
Renal Drug Excretion: Tubular Secretion
Acute Kidney Injury I: Introduction