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Related Experiment Videos

Stereotactic radiosurgery for patients with solid brain metastases: current status.

Ronald E Warnick1, Borimir J Darakchiev, John C Breneman

  • 1Department of Neurosurgery, The Neuroscience Institute, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0515, USA. editor@mayfieldclinic.com

Journal of Neuro-Oncology
|November 6, 2004
PubMed
Summary

Stereotactic radiosurgery (SRS) offers a precise approach for treating brain metastases. This review details SRS indications, outcomes, and management strategies for intracranial tumors.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Background:

  • Brain metastases represent a significant challenge in cancer care.
  • Stereotactic radiosurgery (SRS) has emerged as a key treatment modality.
  • Understanding SRS indications and outcomes is crucial for patient management.

Purpose of the Study:

  • To provide an updated overview of stereotactic radiosurgery (SRS) for intracranial metastatic disease.
  • To discuss the rationale and predictive factors for SRS efficacy.
  • To present clinical algorithms for SRS application in various scenarios.

Main Methods:

  • Review of current literature and clinical experience regarding SRS for brain metastases.
  • Discussion of treatment indications including recurrent disease, WBRT boost, and primary therapy.

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  • Analysis of factors influencing treatment outcomes.

    • Main Results:

    • SRS is effective for recurrent brain metastases, as a boost after WBRT, and as sole therapy for new tumors.
    • Critical factors predicting outcomes are identified.
    • Treatment algorithms are proposed for different clinical situations.

    Conclusions:

    • Stereotactic radiosurgery is a valuable tool in the multidisciplinary management of brain metastases.
    • Tailored treatment algorithms based on clinical factors optimize SRS use.
    • Awareness of potential complications and their management is essential.