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Hepatitis B vaccination in a hyper-endemic tribal community from India: assessment after three years
M V Murhekar1, K M Murhekar, S C Sehgal
1Regional Medical Research Centre, Indian Council of Medical Research (ICMR), Post Bag-13, Port Blair 744101, Andaman and Nicobar Islands, India. mmurhekar@yahoo.com
Abstract:
Hepatitis B infection is highly endemic among the primitive tribes of Andaman and Nicobar Islands, India and it is necessary to initiate hepatitis B vaccination for control of this infection. A pilot project of mass hepatitis B vaccination using indigenously developed vaccine was initiated among Nicobarese tribe of Car Nicobar Island. Sero-protection rates after second and third year were 89% and 85.5%, respectively. The rate of chronic infection in the vaccinated population after three years was 1.86% compared to the pre-vaccination rate of 20.7%. Considering high sero-protection rates and low cost, the indigenous vaccine could be used for vaccination programme in this tribal community.
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