Related Experiment Video
Updated: Aug 16, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
Cancer stem cell biology: from leukemia to solid tumors
1Division of Hematology/Oncology, University of Rochester School of Medicine, 601 Elmwood Avenue, Box 703, Rochester, New York 14642, USA. craig_jordan@urmc.rochester.edu
Stem cells play a key role in cancer development. Understanding stem cell biology is crucial for developing new and effective cancer therapies to combat tumor formation and treatment resistance.
Area of Science:
- Oncology
- Stem Cell Biology
Background:
- Stem cells are increasingly recognized for their integral role in the pathogenesis of various cancers.
- This understanding has significant implications for cancer research and treatment strategies.
Purpose of the Study:
- To highlight the critical role of stem cells in tumor formation.
- To emphasize the need for a comprehensive understanding of stem cell-mediated tumor pathogenesis for improved cancer therapies.
Main Methods:
- Review of current research on stem cells in cancer.
- Analysis of demonstrated roles in hematopoietic, breast, and brain cancers.
Main Results:
- Stem cell properties are integral to tumor pathogenesis in several cancer types.
- Evidence supports stem cell involvement in hematopoietic, breast, and brain cancers.
Conclusions:
- A detailed understanding of stem cells and their role in tumor pathogenesis is essential.
- This knowledge is critical for developing more effective cancer treatment strategies.
Related Concept Videos
Cancers Originate from Somatic Mutations in a Single Cell
Cancer Stem Cells and Tumor Maintenance
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancers Originate from Somatic Mutations in a Single Cell
Cancer Stem Cells and Tumor Maintenance
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Distinctive Features of Adult Stem Cells vs Cancer Stem Cells
Adult stem cells
Adult stem cells are tissue-specific; hence, they divide to develop the tissue from which they originate. One type of adult stem cell is the epithelial stem cell, which gives rise to the keratinocytes in the multiple layers of epithelial cells in the epidermis of the skin. Adult bone marrow has three distinct types of stem cells:...
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

