Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epigenetic germline inheritance.

Suyinn Chong1, Emma Whitelaw

  • 1School of Molecular and Microbial Biosciences, Biochemistry Building-G08, University of Sydney, New South Wales 2006, Australia.

Current Opinion in Genetics & Development
|November 9, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The socioeconomic dimensions of racial inequality in South Africa: A social space perspective.

The British journal of sociology·2024
Same author

GABA<sub>a</sub> receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [<sup>18</sup>F]AH114726.

Nuclear medicine and biology·2020
Same author

Magnetic Resonance Imaging and Micro-Computed Tomography reveal brain morphological abnormalities in a mouse model of early moderate prenatal ethanol exposure.

Neurotoxicology and teratology·2019
Same author

Early gestational ethanol exposure in mice: Effects on brain structure, energy metabolism and adiposity in adult offspring.

Alcohol (Fayetteville, N.Y.)·2018
Same author

Effects of periconceptional maternal alcohol intake and a postnatal high-fat diet on obesity and liver disease in male and female rat offspring.

American journal of physiology. Endocrinology and metabolism·2017
Same author

Radiological studies of fetal alcohol spectrum disorders in humans and animal models: An updated comprehensive review.

Magnetic resonance imaging·2017
Same journal

Temporal trajectories underlying adult neuronal diversity.

Current opinion in genetics & development·2026
Same journal

Transcription regulation of cell fate plasticity - from embryonic development to tissue regeneration.

Current opinion in genetics & development·2026
Same journal

Shared molecular and cellular programs during regeneration of glandular epithelia.

Current opinion in genetics & development·2026
Same journal

Lineage tracing in human cortical development.

Current opinion in genetics & development·2026
Same journal

Cis-regulatory strategies in developmental patterning.

Current opinion in genetics & development·2026
Same journal

GABAergic neuron fate specification and lineage allocation: from development to disorder.

Current opinion in genetics & development·2026
See all related articles

Epigenetic marks can be passed between generations, influencing inheritance patterns. Environmental factors also shape these marks, potentially driving rapid adaptive evolution.

Area of Science:

  • Epigenetics and evolutionary biology

Background:

  • Epigenetic reprogramming aims to erase marks between generations.
  • Incomplete erasure of epigenetic marks can lead to transgenerational inheritance.

Purpose of the Study:

  • To explore the role of incomplete epigenetic erasure and environmental influences in inheritance and evolution.

Main Methods:

  • Review of current knowledge on epigenetic reprogramming.
  • Analysis of inheritance patterns linked to epigenetic marks.
  • Consideration of environmental factors affecting epigenetic establishment.

Main Results:

  • Epigenetic marks are not always fully cleared between generations.
  • Genes with measurable phenotypes show unusual inheritance due to incomplete erasure.

Related Experiment Videos

  • Environmental factors influence epigenetic mark establishment during development.

    • Conclusions:

    • Incomplete epigenetic erasure can cause non-Mendelian inheritance.
    • Environmental influences on epigenetics combined with incomplete erasure offer a mechanism for rapid adaptive evolution.