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Related Experiment Videos

Corneal thickness in children.

Mohamed A W Hussein1, Evelyn A Paysse, Nicholas P Bell

  • 1Cullen Eye Institute, Baylor College of Medicine, Department of Ophthalmology, Texas Children's Hospital, Houston, Texas, USA.

American Journal of Ophthalmology
|November 9, 2004
PubMed
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Pediatric corneal thickness measurements show gradual increases with age, reaching adult levels by age 5-9. These findings provide crucial data for understanding normal pediatric eye development.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Corneal Physiology

Background:

  • Accurate corneal thickness measurements are vital for pediatric eye care.
  • Understanding normal corneal thickness in children is essential for diagnosing various ocular conditions.
  • Previous studies have not comprehensively assessed central and paracentral corneal thickness across diverse pediatric age and racial groups.

Purpose of the Study:

  • To establish normative central and paracentral corneal thickness values in a pediatric cohort.
  • To investigate the consistency of these measurements across different pediatric age strata.
  • To evaluate potential variations in corneal thickness among different racial groups in children.

Main Methods:

  • A prospective observational case series design was employed.

Related Experiment Videos

  • Pachymetry measurements were taken from 198 eyes of 108 children, including central and four paracentral sites.
  • Statistical analyses, including t-tests and ANOVA, were used to compare thickness values across age and racial groups.

    • Main Results:

    • Mean central corneal thickness (CCT) was 549 ± 46 µm; paracentral measurements were significantly thicker.
    • Corneal thickness showed a statistically significant increase with age, reaching adult levels by 5-9 years (ANOVA P = .012).
    • No significant differences in CCT were found among different racial subgroups.

    Conclusions:

    • Pediatric corneal thickness gradually increases with age.
    • Normal adult corneal thickness values are attained between 5 and 9 years of age.
    • These normative data are valuable for pediatric ophthalmological assessments.