Related Experiment Video
Updated: Aug 21, 2026
Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
High incidence of orbital malignant lymphoma in Japanese patients
Kenji Ohtsuka1, Masato Hashimoto, Yasuo Suzuki
1Department of Ophthalmology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, Japan.
Purpose:
To review 244 cases of orbital tumors to determine pathologic findings in Japanese patients.
Design:
Observational case series.
Methods:
We studied the pathology and origin of tumors in the orbit in 244 consecutive Japanese patients with orbital tumors at our institution from 1981 through 2002 (age 0 to 90 years, mean, 48.7 years; 114 men, 130 women).
Results:
The most common tumors were lymphoproliferative diseases (n = 114, 42.5%), including malignant lymphoma (n = 59, 24.1%) and reactive lymphoid hyperplasia (n = 45, 18.4%), pleomorphic adenoma (n = 21, 8.6%), and cavernous hemangioma (n = 18, 7.4%).
Conclusion:
The incidence of lymphoproliferative diseases, especially malignant lymphoma, was very high in Japanese patients.
Related Concept Videos
01:16Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
01:15Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...