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Updated: Aug 21, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
["Mild" cranio-cerebral trauma occasionally have grave psychic sequelae]
1Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Münster. arolt@uni-muenster.de
Abstract:
Cranial injuries appear as neurological symptoms such as unconsciousness and focal neurological deficits. Mild cranio-cerebral traumas, that is, brain injuries without a serious neurotraumatologic symptom complex occuroften in practice. Nevertheless, even slight injuries, above all in the frontal cortical brain areas, can be accompanied by characteristic psycho-organic symptoms ("mild cognitive impairment" in the form of a "pseudoneurasthenic syndrome"). They are detected only after a thorough clinical psychiatric examination with a concomitant neuropsychological test. The diagnostics should be carried out as earlyas possible in order to identify and to immediately treat the respective disease. Chronicity and development of a depressive disorder can be, thus, prevented.
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