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Updated: Aug 21, 2026

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
Published on: November 1, 2019
[Low-carbohydrate or low-fat diet for weight loss--which is better?]
1Else-Kroner-Fresenius-Zentrum für Ernährungsmedizin der TU München, Klinikum Rechts der Isar, Ismaninger Str. 22, D-81675 München. Hauner@wzw.tum.de
Abstract:
Several recent clinical studies show that a low-carbohydrate diet produces a greater initial weight loss than conventional low-fat diets, and is associated with a greater reduction of elevated serum triglycerides. After one year, however, weight loss is similar with both diets. Since the intake of saturated fat is higher on a low-carbohydrate diet, there may be an increased risk of elevated levels of LDL cholesterol, thus furthering atherosclerosis, over the long term. Before low-carbohydrate diets can be considered an equivalent alternative to low-fat diets for the treatment of obesity, long-term clinical trials are urgently required. The greater weight loss under low-carbohydrate diets would appear to be due to a lower caloric intake. Successful weight loss largely depends on restricting the intake of calories, but the supply of essential nutrients should be guaranteed.
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