Related Experiment Video
Updated: Aug 21, 2026

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model
Published on: April 2, 2021
Retinopathy of prematurity and anterior segment complications
Michael S Ibarra1, Antonio Capone
1William Beaumont Hospital, 3535 West 13 Mile Road, Suite 632, Royal Oak, MI 48073, USA.
Insights
Management of retinopathy of prematurity (ROP) has evolved with established screening and treatment protocols. This review details anterior segment complications associated with effective ROP therapies like cryotherapy and laser ablation.
Area of Science:
- Ophthalmology
- Neonatology
- Pediatric Medicine
Background:
- Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
- Advances in neonatal care have increased survival rates of extremely preterm infants, leading to a higher incidence of ROP.
- Established screening and treatment protocols aim for timely intervention in infants at risk.
Purpose of the Study:
- To present anterior segment complications associated with established therapies for retinopathy of prematurity.
- To highlight the risks and challenges in managing ROP.
Main Methods:
- Review of established ROP management strategies.
- Identification and description of anterior segment complications linked to ROP treatments.
Main Results:
- Cryotherapy, laser photoablation, vitrectomy, and scleral buckling are effective ROP treatments.
- These therapeutic interventions carry inherent risks of ocular complications.
- Specific anterior segment complications are detailed in the context of ROP treatment.
Conclusions:
- While effective, ROP therapies can lead to significant anterior segment complications.
- Understanding and anticipating these complications is crucial for optimal patient outcomes.
- Continued research and refined treatment approaches are necessary to minimize ROP-related morbidity.
Abstract:
The management of retinopathy of prematurity (ROP) has changed over the last 20 years. Screening and treatment protocols have been established to provide timely therapy to infants at risk. Cryotherapy, laser photoablation, vitrectomy, and scleral buckling have proven effective but also have inherent risks of complications. The anterior segment complications related to ROP therapy are presented herein.
Related Concept Videos
Diabetic Retinopathy
Glaucoma: Overview
Photoreceptors and Visual Pathways

