Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relation between objective and subjective measures of bladder dysfunction in multiple sclerosis.

J Jolijn Kragt1, Erwin L J Hoogervorst, Bernard M J Uitdehaag

  • 1Department of Neurology, VU University Medical Center, De Boelelaan 1117, PO Box 7057 1007 MB Amsterdam, The Netherlands. JJ.Kragt@vumc.nl

Neurology
|November 10, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Individual Variability of CD19+ B-Cell Repopulation in People With Multiple Sclerosis Treated With Extended Interval Dosing of Ocrelizumab.

European journal of neurology·2026
Same author

Mediation Analysis Between Brain Age, Disease-Modifying Factors, and Disability and Cognitive Performance in Multiple Sclerosis.

Neurology·2026
Same author

The impact of Information processing speed on visuospatial memory encoding and retrieval in multiple sclerosis.

Journal of clinical and experimental neuropsychology·2026
Same author

Breaking the PROMISE: poor association between brain volume loss and clinical disability worsening over 2 years of follow-up in primary progressive multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

Spheres of uncertainty: A phenomenological inquiry into healthcare practice surrounding the care for people with relapsing-remitting multiple sclerosis.

Qualitative research in medicine & healthcare·2026
Same author

Association of Brain Age With Physical Disability and Cognitive Impairment in People With Multiple Sclerosis of the Same Age.

Neurology·2025

In multiple sclerosis (MS) patients, subjective urinary symptom scores like EDSS and GNDS do not predict bladder emptying issues. Ultrasound for post-void residual volume is recommended for all MS patients, regardless of symptoms.

Area of Science:

  • Neurology
  • Urology

Background:

  • Multiple sclerosis (MS) frequently causes urinary dysfunction, impacting patient quality of life.
  • Current methods for assessing bladder dysfunction in MS patients include subjective symptom scores and objective measurements.

Purpose of the Study:

  • To evaluate the correlation between subjective urinary symptom scores and objective measures of bladder dysfunction in multiple sclerosis patients.
  • To determine the predictive value of the Expanded Disability Status Scale (EDSS) and Guy's Neurological Disability Scale (GNDS) for postvoiding residual urine volume.

Main Methods:

  • The study included 297 patients diagnosed with multiple sclerosis.
  • Urinary symptoms were assessed using the bowel/bladder Functional System (FS) score of the EDSS and the bladder dysfunction score of the Guy's Neurological Disability Scale (GNDS).

Related Experiment Videos

  • Objective measurement of bladder dysfunction was performed by assessing postmicturition residual volume using ultrasound.

    • Main Results:

    • The EDSS and GNDS scores showed no significant value in predicting the presence of a clinically relevant postvoiding residual urine volume.
    • A significant number of multiple sclerosis patients may have asymptomatic bladder dysfunction.

    Conclusions:

    • Subjective assessments of urinary symptoms are insufficient for identifying significant bladder emptying problems in multiple sclerosis.
    • Routine ultrasound assessment of postvoid residual volume is recommended for all multiple sclerosis patients to detect asymptomatic bladder dysfunction.