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Related Experiment Videos

Agreement between three commercially available instruments for measuring short-term heart rate variability.

G R H Sandercock1, C Shelton, P Bromley

  • 1Research Centre for Health Studies, Buckinghamshire Chilterns University College, Newlands Park, Chalfont St Giles, Buckinghamshire, HP8 4AD, UK.

Physiological Measurement
|November 13, 2004
PubMed
Summary

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Measures of heart rate variability (HRV) from three devices showed excellent agreement initially. However, further analysis revealed significant variations and bias due to differing recording protocols, impacting result comparability.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Physiology

Background:

  • Heart rate variability (HRV) is a key indicator of autonomic nervous system function.
  • Numerous commercial instruments exist for HRV measurement, but their inter-device agreement is poorly understood.

Purpose of the Study:

  • To assess the agreement between heart rate variability measurements from three distinct commercial instruments.
  • To identify potential discrepancies and biases in HRV data generated by different devices.

Main Methods:

  • Simultaneous electrocardiogram (ECG) recordings were obtained from 30 subjects under three resting conditions.
  • Three commercially available HRV analyzers were used concurrently.
  • Intraclass correlation coefficients (ICCs) and Bland-Altman limits of agreement were employed for statistical analysis.

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Main Results:

  • Initial ICC analysis suggested excellent agreement (ICC > 0.75) across all instruments and conditions.
  • However, Bland-Altman analysis revealed substantial variations and systematic bias between specific instruments.
  • Discrepancies were attributed to differences in ECG recording protocols, not operator timing.

Conclusions:

  • Despite initial indications of good agreement, commercial HRV instruments may produce incomparable results due to variations in recording protocols.
  • Reporting levels of agreement is crucial when using different instruments within the same study, for multi-center designs, or when comparing results across studies.
  • Standardized recording protocols are recommended to enhance the reliability and comparability of HRV measurements.