Related Experiment Videos
Pigmented penile macules.
Mrinalini Mahto1, Paul David Woolley, John Ashworth
1OPD B, Genitourinary Medicine Department, Stepping Hill Hospital, Poplar Grove, Stockport SK2 7JE, UK. drmahto@onetel.com
International Journal of STD & AIDS
|November 13, 2004
Summary
Management of pigmented penile macules is debated. Some advocate removal due to melanoma risk, while others deem it unnecessary, favoring individualized diagnosis via biopsy.
Area of Science:
- Dermatology
- Urology
- Oncology
Background:
- Pigmented penile macules present a diagnostic and management dilemma.
- Conflicting opinions exist regarding the necessity of prophylactic excision versus conservative management.
Purpose of the Study:
- To review the literature on the natural history of pigmented penile macules.
- To assess the risk of melanoma development on the penis.
- To evaluate current management strategies for pigmented penile macules.
Main Methods:
- Literature review of studies on pigmented penile macules, penile melanoma, and their management.
- Analysis of differing expert opinions on prophylactic excision.
- Discussion of individualized management approaches including biopsy.
Main Results:
- Two main schools of thought exist: prophylactic excision versus conservative management.
- Some experts consider pigmented penile macules on the genitalia as junctional nevi with high malignant potential.
- Others argue that most penile melanomas arise de novo, making prophylactic excision unnecessary.
Conclusions:
- Management of pigmented penile macules should be individualized.
- Multiple biopsies are recommended to establish an accurate diagnosis.
- Further research is needed to clarify the natural history and melanoma risk.