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Bacterial isolates in the sick young infant in Ile-Ife, Nigeria

E A Adejuyigbe1, A K Ako-Nai, B Adisa

  • 1Department of Pediatrics, Obafemi Awolowo University, Ile-Ife, Nigeria. ebunadejuyigbe@hotmail.com

Journal of Tropical Pediatrics
|November 13, 2004
PubMed

Insights

Bacterial infections are common in sick young infants, with Gram-positive bacteria like Staphylococcus aureus being most prevalent. Most isolates showed sensitivity to common antibiotics, but resistance to cotrimoxazole was noted.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Bacterial infections pose a significant threat to young infants.
  • Understanding local pathogen prevalence and antibiotic sensitivity is crucial for effective treatment.

Purpose of the Study:

  • To identify bacterial pathogens and their antibiotic sensitivity profiles in sick young infants.
  • To guide empirical antibiotic therapy in this vulnerable population.

Main Methods:

  • Prospective study screening 121 sick young infants for bacterial infections and septicemia over 5 months.
  • Bacterial isolates were identified, and antibiotic sensitivity testing was performed.

Main Results:

  • A high prevalence of bacterial infection (77.7%) and septicemia (57.4%) was observed.
  • Gram-positive organisms, particularly Staphylococcus aureus (61.2%), were the most common isolates.
  • All isolates were sensitive to ofloxacin; most were sensitive to commonly used antibiotics, but resistance to cotrimoxazole was significant.

Conclusions:

  • Bacterial infections are highly prevalent in young infants in Ile-Ife, Nigeria.
  • Gram-positive bacteria are the primary cause and remain sensitive to many standard antibiotics.
  • Gentamicin and cloxacillin or erythromycin are recommended as first-line treatments.

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