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Related Experiment Videos

Calvarial tuberculosis.

D K Stones1, C J Schoeman

  • 1Department of Paediatrics and Child Health, University of the Free State, Bloemfontein, South Africa. gnpddks.md@mail.uovs.ac.za

Journal of Tropical Pediatrics
|November 13, 2004
PubMed
Summary
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Tuberculosis of the skull is a rare condition. This report details two pediatric cases with skull lesions, orbital swelling, and scalp ulcers, alongside vertebral and lung tuberculosis.

Area of Science:

  • Pediatric infectious diseases
  • Skeletal tuberculosis
  • Craniofacial imaging

Background:

  • Tuberculosis (TB) is a global health concern.
  • Skull tuberculosis is an exceptionally rare manifestation of Mycobacterium tuberculosis infection.
  • Diagnosis often relies on a combination of clinical presentation and imaging.

Observation:

  • Two children presented with distinct clinical signs of cranial tuberculosis.
  • Case 1: Orbital and scalp swellings with lytic skull lesions on X-ray.
  • Case 2: Chronic discharging scalp ulcers and lytic skull lesions.

Findings:

  • Both patients exhibited lytic skull lesions, indicating direct bone involvement.
  • Vertebral and lung tuberculosis were concurrently diagnosed in both cases, suggesting disseminated disease.

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  • The clinical presentations, though different, were consistent with cranial TB.

    • Implications:

    • Highlights the importance of considering rare diagnoses like skull TB in children with suggestive symptoms.
    • Emphasizes the utility of imaging in identifying osseous TB.
    • Underscores the need for prompt diagnosis and treatment of disseminated TB to prevent severe complications.