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Updated: Aug 10, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Severe obstructive sleep apnea in a patient with spinal muscle atrophy
Michael Puruckherr1, Jay B Mehta, Mirle R Girish
1Veterans Affairs Medical Center 111-B, PO Box 4000, Mountain Home, TN 37684-4000, USA. Ryland.Byrd@med.va.gov
Abstract:
Patients with spinal muscle atrophy (SMA) who survive to adulthood experience a slow, continuous loss of motor function but typically have a normal life expectancy. These patients, however, require vigilance on the part of their health-care providers to reverse treatable disorders to maintain a satisfactory quality of life. We report on a patient with obstructive sleep apnea and type 3 SMA. The treatment of his sleep-disordered breathing resulted in the resolution of symptoms that were initially attributed to his neuromuscular disease.
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