Related Experiment Video
Updated: Aug 21, 2026
How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners
Published on: May 31, 2018
A study on the effect of lead on event-related potentials among lead-exposed workers
Mamoru Hirata1, Hiroshi Kosaka, Toshiaki Yoshida
1Department of Research Planning, National Institute of Industrial Health, Nagao 6-21-1, Tama-ku, Kawasaki 214-8585, Japan.
Objectives:
In order to clarify the effect of lead on higher cerebral functions, lead-exposed workers (Pb group) and controls were examined for event-related potentials.
Subjects And Methods:
Fourteen lead-exposed workers with a mean age of 57.1 yr (SD=4.27, range 48-64; lead concentration of whole blood ranged from 33 to 106 microg/dl with a mean of 58.6 and SD 28.6 microg/dl) and 19 age-matched control workers with a mean age of 57.3 yr (SD=4.80, range 48-65) were examined. Visual P300 was recorded by button pushing to the target image (minute checkerboard pattern, 20%), and the NO-GO potential by no button pushing to the target image (same as above, 50%).
Results:
Latencies of P300 in the Pb group (475+/-46.0 ms) were significantly delayed compared with those in controls (407+/-42.4 ms, p<0.01 by Student's t test). Amplitudes of the NO-GO potential in the Pb group (4.59+/-2.04 microV) significantly increased compared with those in the controls (3.18+/-1.41 microV, p<0.05).
Conclusion:
The finding suggests that lead exposure affects high cerebral functions of cognition and attention, but is unclear in suppression of movement.
More Related Videos
11:39Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique
Published on: September 7, 2022
10:02Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
Published on: March 12, 2020