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Endometriosis with FDG uptake on PET
Louis Jeffry1, Khaldoun Kerrou, Sophie Camatte
1Service de Chirurgie Gynécologique et Cancérologique, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
|November 16, 2004
Summary
18F-fluorodeoxyglucose positron emission tomography (FDG-PET) uptake in endometriosis can be misleading. This case report shows FDG-PET uptake in endometriosis may reflect inflammation, not malignancy, aiding diagnosis.
Area of Science:
- Gynecologic Oncology
- Diagnostic Imaging
- Nuclear Medicine
Background:
- The diagnostic utility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in endometriosis remains underexplored.
- Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus.
Observation:
- A patient with pelvic pain presented with findings suggestive of liver hemangioma or endometriosis, and an ovarian cyst.
- FDG-PET revealed uptake in the paravesical area, later confirmed as endometriosis during laparoscopy.
- Recurrent symptoms of dyspareunia and rectal pain were linked to endometriosis nodules.
Findings:
- FDG-PET uptake in this endometriosis case was attributed to inflammation rather than neoplastic processes.
- Successful surgical resection and GnRH agonist treatment led to symptom resolution and normalized imaging.
- The case highlights similarities between endometriosis and neoplastic lesions in FDG-PET imaging.
Implications:
- FDG-PET may show false-positive results in endometriosis due to inflammatory components.
- Understanding the inflammatory aspect of endometriosis is crucial for accurate FDG-PET interpretation.
- This case underscores the importance of correlating imaging findings with clinical presentation in endometriosis diagnosis.