Related Experiment Video
Updated: Aug 6, 2026

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft
Published on: February 14, 2022
Cardiac transplantation
1College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. hack_shanewise@emoryhealthcare.org
Insights
Cardiac transplantation offers a life-saving therapy for end-stage heart failure. Anesthetic management is crucial for successful heart transplant operations, despite donor heart scarcity.
Area of Science:
- Cardiology
- Transplantation Medicine
- Anesthesiology
Background:
- Cardiac transplantation is an established treatment for select patients with end-stage heart failure.
- The primary limitation to cardiac transplantation is the insufficient availability of suitable donor organs.
- This review focuses on adult cardiac transplantation procedures.
Purpose of the Study:
- To review the current state of adult cardiac transplantation.
- To emphasize the critical anesthetic considerations during heart transplant surgery.
Main Methods:
- Literature review of adult cardiac transplantation.
- Focus on anesthetic management protocols for heart transplant operations.
Main Results:
- Cardiac transplantation is a viable therapy for specific end-stage heart failure patients.
- Anesthetic management plays a pivotal role in the success of heart transplantation.
Conclusions:
- Despite donor organ limitations, cardiac transplantation remains a vital therapeutic option.
- Expert anesthetic care is essential for optimizing outcomes in heart transplant recipients.
Abstract:
Cardiac transplantation is a proven, accepted mode of therapy for selected patients with end-stage heart failure, but the inadequate number of suitable donor hearts available ultimately limits its application. This chapter reviews adult cardiac transplantation, with an emphasis on the anesthetic considerations of the heart transplant operation itself.
Related Concept Videos
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Cardiomyopathy V: Interprofessional Care
Kidney Transplant I: Introduction

