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Related Experiment Videos

Modified Ross procedure using a conduit with a synthetic valve.

Shin Takabayashi1, Hideaki Kado, Yuichi Shiokawa

  • 1Department of Cardiovascular Surgery, Fukuoka Children's Hospital, 2-5-1 Tojin-machi, Chuo-ku, Fukuoka 810-0063, Japan. shin1111@clin.medic.mie-u.ac.jp

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|November 16, 2004
PubMed
Summary

This study shows that using a synthetic valved conduit in a modified Ross procedure is a safe and effective alternative to homografts for right ventricular outflow tract reconstruction in older children. Early results indicate good valvular and right ventricular function.

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Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Science
  • Pediatric Cardiology

Background:

  • The Ross procedure typically uses a homograft pulmonary valve, but availability issues necessitate alternatives.
  • Synthetic valved conduits offer a potential solution to homograft scarcity in right ventricular outflow tract reconstruction.

Purpose of the Study:

  • To evaluate the early outcomes of a modified Ross procedure using a synthetic valved conduit for right ventricular outflow tract reconstruction.
  • To assess valvular and right ventricular function in patients receiving a synthetic valve conduit.

Main Methods:

  • Eleven pediatric patients (ages 5-22) underwent right ventricular outflow tract reconstruction with a hand-fashioned synthetic valved conduit (polytetrafluoroethylene or Dacron).
  • Indications included aortic stenosis and/or regurgitation.

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  • Conduits were constructed from a 0.1 mm thick polytetrafluoroethylene sheet or Dacron graft.
  • Main Results:

    • No in-hospital or late mortality was observed.
    • All artificial valves remained functional post-surgery.
    • Postoperative echocardiography showed a mean pressure gradient of 11.4+/-11.1 mmHg across the synthetic valve with no moderate or severe regurgitation.

    Conclusions:

    • A modified Ross procedure utilizing a synthetic valved conduit is effective for right ventricular outflow tract reconstruction.
    • This approach is particularly beneficial for older children, offering a viable alternative to homografts.