Related Experiment Video
Updated: Aug 21, 2026

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
Published on: March 29, 2018
Biologic fixation and bone ingrowth
Scott M Sporer1, Wayne G Paprosky
1Orthopaedic Surgery, Rush Medical College, 1725 West Harriston Street, Suite 1063, Chicago, IL 60612, USA. ssporer@hotmail.com
Abstract:
Total hip arthroplasty has provided thousands of patients with pain relief and has improved their quality of life. Advances in orthopaedic surgical techniques and implant biomaterials now allow predictable surgical results in most patients. Despite the overwhelming success of this surgical procedure, the debate continues surrounding the optimal choice of implants. Femoral and acetabular implants with varying geometries and fixation methods are currently available. Acrylic bone cement has been used extensively in the past for acetabular and femoral fixation. This mode of component fixation currently remains the technique used most frequently throughout Europe and has shown excellent long-term results. Problems inherent with acrylic bone cement, however, have encouraged other surgeons to use alternative surfaces to allow biologic fixation.
Related Concept Videos
Bone Remodeling
The Bone Matrix
Osteoclasts in Bone Remodeling

