Related Experiment Video
Updated: Aug 20, 2026

Procurement for a Vascularized and Reinnervated Abdominal Wall Allotransplantation
Published on: July 18, 2025
Early reconstruction of the abdominal wall in giant omphalocele
Mario Zama1, Simona Gallo, Luigino Santecchia
1Plastic Surgery Unit, Children's Hospital Bambino Gesù, Piazza S. Onofrio 4, 00165 Rome, Italy. mariozama@virgilio.it
Insights
Omphalocele, a common abdominal wall defect, has high mortality. Early surgical closure within 10 days is crucial. This study presents a technique using bipedicled abdominal skin flaps for defect repair.
Area of Science:
- Pediatric Surgery
- Congenital Abnormalities
- Surgical Techniques
Background:
- Omphalocele is the most frequent congenital defect affecting the abdominal wall.
- High mortality rates (20-70%) are associated with omphalocele.
- Timely surgical intervention, specifically abdominal wall closure within 10 days of birth, is critical for patient survival.
Observation:
- The study focuses on the surgical management of omphalocele.
- A specific surgical technique involving bipedicled flaps of abdominal skin is described.
- This method is applied after the reduction of all protruding viscera.
Findings:
- The described technique utilizes two bipedicled flaps of abdominal skin.
- These flaps are employed to reconstruct the midline abdominal wall defect.
- The procedure is performed once visceral reduction is achieved.
Implications:
- This surgical approach offers a method for omphalocele repair.
- Successful early closure can improve outcomes for infants with omphalocele.
- The technique aims to reduce the high mortality associated with this condition.
Abstract:
Omphalocele is the most common congenital defect of the abdominal wall. Mortality rate is between 20 and 70% and early closure of the abdominal wall, within 10 days of life, is vital to the successful outcome of the surgical treatment. The authors describe the use of two bipedicled flaps of abdominal skin to correct the defect of the midline as soon as the reduction of all viscera has been accomplished.
