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Updated: Aug 20, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Anterior and posterior cruciate ligament injuries
Jeffrey R Brown1, Thomas H Trojian
1Department of Family Medicine, University of Connecticut Health Center/St. Francis Hospital and Medical Center, 99 Woodland Street, Hartford, CT 06105, USA. jbrown@stfranciscare.org
Abstract:
Knee pain is a common complaint in the primary care setting, and ACL and PCL injuries are common causes of knee pain. Therefore, it is important for the primary care physician to be skilled in the diagnosis and initial management of these injuries and to be aware of potential associated knee injuries. By understanding the history, mechanism of injury, physical examination maneuvers, and imaging modalities related to ACL and PCL injuries, primary care physicians can prepare themselves to make an accurate diagnosis. Then they can counsel the patients on the available treatments, initiate conservative treatment if appropriate, and facilitate an effective referral to a primary care sports medicine physician or orthopedic surgeon.
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