Endovascular interventions in iliac and infrainguinal occlusive artery disease

Johannes Ruef1, Manfred Hofmann, Jürgen Haase

  • 1Red Cross Hospital Cardiology Center, Frankfurt, Germany. j.ruef@kardiocentrum-ffm.de

Insights

Endovascular procedures effectively treat peripheral artery disease, but long-term success varies by artery location. New strategies are needed to improve patency rates and update current guidelines.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Endovascular Medicine

Background:

  • Percutaneous endovascular procedures are common for symptomatic peripheral occlusive artery disease.
  • High technical success rates are observed, but long-term patency differs based on anatomical location (iliac, femoropopliteal, infrapopliteal).

Purpose of the Study:

  • To review the effectiveness of endovascular treatments for peripheral occlusive artery disease.
  • To discuss current limitations and emerging strategies for improving long-term outcomes, particularly in challenging infrainguinal interventions.

Main Methods:

  • Review of current literature on percutaneous endovascular procedures for peripheral occlusive artery disease.
  • Analysis of factors influencing long-term patency rates in different arterial segments.
  • Discussion of novel and investigational treatment modalities.

Main Results:

  • Iliac artery interventions, especially with nitinol stents, show good long-term patency.
  • Infrainguinal interventions face challenges with high restenosis rates, with optimal treatment methods still debated.
  • Emerging techniques like drug-eluting stents and covered stent grafts show promise.

Conclusions:

  • While endovascular techniques are successful, long-term patency varies significantly by anatomical region.
  • High restenosis rates in femoropopliteal and infrapopliteal arteries necessitate further research and development of new strategies.
  • Current consensus guidelines require reevaluation based on accumulated data and advancements in peripheral interventions.

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