Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Granulomatous uveitis and CREST syndrome: a case study].

M Courtade1, J J Gicquel, M Mercie

  • 1Service d'Ophtalmologie, CHU de Poitiers.

Journal Francais D'Ophtalmologie
|November 18, 2004
PubMed
Summary

This case report details recurrent granulomatous panuveitis in a patient with CREST syndrome. Prompt corticosteroid treatment led to significant visual recovery, highlighting this rare ocular association.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and safety of micropulse versus continuous wave transscleral diode cyclophotocoagulation in treating glaucoma.

Journal francais d'ophtalmologie·2025
Same author

Management of women with abnormal cervical cytology: Update of French guidelines after the implementation of HPV screening.

European journal of obstetrics, gynecology, and reproductive biology·2025
Same author

French national protocol for diagnosis and management of epidermal necrolysis in adults (Stevens-Johnson syndrome and toxic epidermal necrolysis).

Annales de dermatologie et de venereologie·2024
Same author

[Risk factors for failure of pre-cut eye bank UT-DSAEK grafts].

Journal francais d'ophtalmologie·2023
Same author

[Vector analysis of astigmatism correction in femtosecond laser-assisted arcuate keratotomy for extreme astigmatism after penetrating keratoplasty].

Journal francais d'ophtalmologie·2022
Same author

[Management of ocular toxoplasmosis in France: Results of a modified Delphi study].

Journal francais d'ophtalmologie·2022

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Connective tissue diseases can manifest with ocular complications.
  • CREST syndrome, a variant of systemic sclerosis, presents unique challenges in diagnosis and management.
  • Ocular inflammation, such as uveitis, can be a rare but significant manifestation of CREST syndrome.

Observation:

  • A 74-year-old female with CREST syndrome developed recurrent unilateral granulomatous panuveitis in a pseudophakic eye post-cataract surgery.
  • Clinical findings included decreased visual acuity (20/400), retrodescemetic and intraocular lens precipitates, vitreous haze, papillary edema, and cystoid macular edema.
  • Fluorescein angiography confirmed macular edema, aiding in diagnosis.

Findings:

  • Topical corticosteroid therapy and mydriatics effectively controlled the uveitis within weeks.

Related Experiment Videos

  • The patient experienced substantial visual recovery to 20/30.
  • Extensive workup excluded other causes of granulomatous uveitis and chronic endophthalmitis.

    • Implications:

    • This case underscores the importance of considering CREST syndrome in the differential diagnosis of granulomatous panuveitis, especially in patients with a history of connective tissue disease.
    • The successful management with topical corticosteroids suggests a favorable prognosis for this rare ocular manifestation.
    • Further research into the pathogenesis and optimal treatment strategies for uveitis associated with CREST syndrome is warranted given its rarity.