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16:49
Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
Published on: July 16, 2012
The CCR5Delta32 allele is associated with reduced liver inflammation in hepatitis C virus infection
1Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, Jerusalem, Israel.
Abstract:
CCR5Delta32 is a deletion mutation in the chemokine receptor CCR5. Liver inflammatory activity was found to be significantly reduced (P = 0.005) in Jewish Israeli patients infected with the hepatitis C virus (HCV) carrying the CCR5Delta32 allele. The CCR5Delta32 allele does not alter susceptibility to HCV infection; however, it may play a role in the progression and outcome of the disease.
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