Ophthalmomyiasis: a review with special reference to Cochliomyia hominivorax

Ophthalmomyiasis, infestation of the eye by dipterous fly larvae, may result in sequelae ranging from minor irritation to blindness, disfigurement, and death. Infestation with Cochliomyia hominivorax, a medically significant and economically important species, exemplifies the mechanisms by which larvae can cause tissue damage. Although clinical history may be suggestive of ophthalmomyiasis, the definitive diagnosis requires direct observation of larvae. Treatment of ophthalmomyiasis involves removal or destruction of the larvae, if alive, and appropriate management of any sequelae. Preventive measures may not always be successful.