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Granulomatous prostatitis due to Mycobacterium avium complex.
1Department of Medicine, Brown University, Providence, Rhode Island.
Summary
Granulomatous prostatitis caused by nontuberculous mycobacteria is rare. This case highlights Mycobacterium avium complex infection in an immunocompetent man presenting with sterile pyuria and positive skin test.
Area of Science:
- Infectious Diseases
- Urology
- Microbiology
Background:
- Granulomatous infections of the genitourinary tract are uncommon.
- Nontuberculous mycobacteria (NTM) are an even rarer cause of such infections.
Observation:
- A case of prostatitis in an immunocompetent male is presented.
- The patient exhibited sterile pyuria and a positive Mantoux skin test.
- Pathologic examination revealed necrotizing granulomas with acid-fast bacilli in the prostate.
Findings:
- The causative agent was identified as Mycobacterium avium complex (MAC).
- Repeated urine cultures confirmed the presence of M. avium complex before treatment initiation.
Implications:
- This case expands the understanding of genitourinary granulomatous infections.
- It underscores the importance of considering NTM, specifically M. avium complex, in the differential diagnosis of sterile pyuria and prostatitis, even in immunocompetent individuals.
- Highlights the diagnostic utility of histopathology and microbiology in identifying rare pathogens.
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