Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Refractive adaptation in amblyopia: quantification of effect and implications for practice.

C E Stewart1, M J Moseley, A R Fielder

  • 1Department of Visual Neuroscience, Imperial College London, Charing Cross Campus, Margravine Road, London W6 8RP, UK. c.stewart@imperial.ac.uk

The British Journal of Ophthalmology
|November 19, 2004
PubMed
Summary

Spectacle correction significantly improves visual acuity in children with unilateral amblyopia, a process called refractive adaptation. This visual improvement occurs regardless of amblyopia type or age, potentially enhancing compliance with other treatments like patching.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Effect of Carbohydrate Restriction on Lipids, Lipoproteins, and Nuclear Magnetic Resonance-Based Metabolites: CALIBER, a Randomised Parallel Trial.

Nutrients·2023
Same author

Changes in Gut Bacterial Translation Occur before Symptom Onset and Dysbiosis in Dextran Sodium Sulfate-Induced Murine Colitis.

mSystems·2021
Same author

Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics.

Scientific reports·2021
Same author

DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity.

Scientific reports·2020
Same author

Stable C isotope data of southern mixed-grass prairie vegetation from Oklahoma, United States.

Data in brief·2020
Same author

Short-term, but not acute, intake of New Zealand blackcurrant extract improves insulin sensitivity and free-living postprandial glucose excursions in individuals with overweight or obesity.

European journal of nutrition·2020

Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Vision Science

Background:

  • Amblyopia, or
  • lazy eye
  • is a developmental disorder of vision.
  • Unilateral amblyopia affects one eye and can lead to reduced visual acuity.
  • Refractive adaptation, the visual response to spectacle correction, is a key factor in amblyopia management.

Purpose of the Study:

  • To investigate the visual response to spectacle correction (refractive adaptation) in children with unilateral amblyopia.
  • To analyze how age, amblyopia type, and refractive error influence refractive adaptation.
  • To differentiate the effects of refractive adaptation from other amblyopia treatments.

Main Methods:

  • Collected visual acuity data (logMAR) from newly diagnosed children with unilateral amblyopia and significant refractive error.

Related Experiment Videos

  • Measured corrected visual acuity in amblyopic and fellow eyes at baseline and repeated measurements every 6 weeks for 18 weeks.
  • Analyzed visual acuity changes based on age, amblyopia type (anisometropia, strabismus, mixed), and refractive error categories.

    • Main Results:

    • Significant improvement in corrected visual acuity (0.24 logMAR, p<0.001) was observed in amblyopic eyes over 18 weeks.
    • Visual acuity gains from refractive adaptation did not significantly differ by amblyopia type (anisometropia, mixed, strabismic) or age group (under 4, 4-6, over 6 years).
    • The study included 65 children with a mean age of 5.1 years.

    Conclusions:

    • Refractive adaptation is a distinct and significant component of amblyopia treatment.
    • Understanding refractive adaptation is crucial for evaluating the efficacy of therapies like occlusion and penalization.
    • Early refractive correction can improve visual acuity, potentially enhancing patient compliance and reducing the need for prolonged patching.