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Updated: Aug 20, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Management of patients who have relapses in multiple sclerosis
1Neuro-inflammatory Unit, Ground Floor, University Hospital of Wales, Heath Park, Cardiff, Wales, UK.
Abstract:
Multiple sclerosis (MS) is a chronic neurological condition, which disrupts the typical functions and daily activities of those affected. Approximately 80% of those diagnosed will follow a relapsing/remitting disease course at diagnosis. Patients with relapsing/remitting MS can expect to have episodes of relapse or an exacerbation of the disease and its variety of symptoms. Management of such episodes has always been open to the preferences of the healthcare professionals involved. The aim of this article is to review the evidence that exists to support current practice in the management of patients during a relapse and to evaluate how this evidence can be incorporated into patient care. The article begins by giving an overview of MS, and continues by determining what a relapse is and discussing the speculated triggers of relapse. Methods of treating relapse are then explored. It concludes by highlighting the strongest evidence-based method for treating relapses, and by emphasizing the need for further research into the pharmaceutical and non-pharmaceutical management of MS relapses.
Insights
This review examines evidence-based practices for managing multiple sclerosis (MS) relapses. It highlights the strongest treatment methods and calls for more research into pharmaceutical and non-pharmaceutical interventions for MS exacerbations.
Area of Science:
- Neurology
- Clinical Medicine
Background:
- Multiple sclerosis (MS) is a chronic neurological disease impacting daily life.
- Most MS patients (80%) experience a relapsing-remitting course.
- Relapses involve exacerbations of MS symptoms, requiring effective management.
Purpose of the Study:
- To review existing evidence supporting current practices in managing MS relapses.
- To evaluate how this evidence can be integrated into patient care.
- To explore triggers and treatment methods for MS relapses.
Main Methods:
- Literature review of evidence-based practices for MS relapse management.
- Analysis of current treatment approaches.
- Discussion of potential relapse triggers.
Main Results:
- Identifies the strongest evidence-based method for treating MS relapses.
- Evaluates the incorporation of evidence into patient care.
- Highlights gaps in current management strategies.
Conclusions:
- Current MS relapse management relies on professional preferences.
- There is a need for further research in both pharmaceutical and non-pharmaceutical MS relapse management.
- Evidence-based strategies are crucial for optimizing patient care during relapses.
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