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Related Experiment Videos

Drug use among functionally active, aged, ambulatory people.

J C Delafuente1, J R Meuleman, M Conlin

  • 1Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville.

The Annals of Pharmacotherapy
|February 1, 1992
PubMed
Summary
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This study found that active, healthy older adults (76-96 years) did not excessively use medications, though adverse drug effects were common. Extreme age does not always mean frailty or polypharmacy.

Area of Science:

  • Gerontology
  • Pharmacoepidemiology
  • Geriatric Medicine

Background:

  • Limited pharmacoepidemiology research includes very old subjects, often mixing healthy and ill individuals.
  • Interpretation of drug use in the elderly is challenging due to heterogeneous health statuses.
  • Previous studies often included mixed populations, limiting insights into drug use among healthy, active very old individuals.

Purpose of the Study:

  • To examine drug utilization patterns in a cohort of active, relatively healthy, very old individuals.
  • To assess the prevalence of adverse drug effects in this specific demographic.
  • To investigate the relationship between drug use and health status, including falls, in the elderly.

Main Methods:

  • A study population of 61 volunteers aged 76-96 years attending a national convention.

Related Experiment Videos

  • Data collection included medication histories (prescription and non-prescription), blood biochemistry, and mental status examinations.
  • Focus on ambulatory, relatively healthy, and functional very old participants.

    • Main Results:

    • The average use was 2.02 prescription and 1.85 non-prescription drugs per person.
    • Over 25% used no prescription drugs; two-thirds used two or fewer.
    • 16% of those on prescription medications reported adverse effects; falling prevalence did not correlate with drug use patterns.

    Conclusions:

    • Very old, healthy, and functional individuals do not necessarily exhibit excessive drug use.
    • Adverse drug effects remain a concern even in this population.
    • Advanced age alone does not invariably lead to sickness, frailty, or polypharmacy.