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Left ventricular noncompaction cardiomyopathy in association with trisomy 13

C J McMahon1, A C Chang, R H Pignatelli

  • 1Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA. cmcmahon@bcm.tmc.edu

Pediatric Cardiology
|November 19, 2004
PubMed

Insights

Left ventricular noncompaction (LVNC) is a rare cardiomyopathy. This case is the first to report LVNC in a child diagnosed with trisomy 13, expanding knowledge of this condition.

Area of Science:

  • Cardiology
  • Genetics
  • Pediatrics

Background:

  • Left ventricular noncompaction (LVNC) is increasingly recognized as a distinct cardiomyopathy.
  • Over 100 pediatric cases of LVNC have been documented.
  • LVNC is often associated with genetic or metabolic disorders.

Observation:

  • This report details a unique case of LVNC in a pediatric patient.
  • The patient was diagnosed with trisomy 13.

Findings:

  • This is the first documented instance of LVNC occurring in a child with trisomy 13.
  • The findings suggest a potential link between trisomy 13 and LVNC development.

Implications:

  • This case expands the known clinical spectrum of trisomy 13.
  • It highlights the importance of considering LVNC in children with trisomy 13.
  • Further research is warranted to understand the underlying mechanisms connecting trisomy 13 and LVNC.

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