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Brachioradial pruritus--an enigmatic entity.
1Department of Dermatology, St. Vincent's University Hospital, Dublin, Ireland. rbmbarry@hotmail.com
Clinical and Experimental Dermatology
|November 20, 2004
Summary
Brachioradial pruritus (BRP) causes upper arm itching, often linked to cervical spine issues. Topical capsaicin and amitriptyline showed effectiveness in managing this condition.
Area of Science:
- Neurology
- Dermatology
Background:
- Brachioradial pruritus (BRP) is an uncommon condition causing itching on the upper arms.
- It classically affects skin over the brachioradialis muscles.
Purpose of the Study:
- To describe clinical features and treatment outcomes for seven patients with BRP.
- To explore potential etiological factors including cervical osteoarthritis and ultraviolet radiation.
Main Methods:
- Case series describing seven patients diagnosed with BRP.
- Assessment of radiological evidence of cervical vertebral osteoarthritis.
- Evaluation of treatment responses to topical capsaicin and amitriptyline.
- Observation of potential triggers like ultraviolet radiation (UVR).
Main Results:
- Six out of seven patients had upper limb involvement, four bilateral.
- Cervical vertebral osteoarthritis was present in five patients.
- Four patients experienced significant relief with topical capsaicin.
- Two additional patients improved with amitriptyline.
- Three patients reported exacerbation with UVR exposure.
Conclusions:
- BRP may be associated with underlying neurological cervical injury.
- Ultraviolet radiation can act as a trigger in some individuals.
- Topical capsaicin and amitriptyline are potential treatment options for BRP.