Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Splenic infarction during acute malaria.

Philippe Bonnard¹, Jean-Baptiste Guiard-Schmid, Michel Develoux

¹Service de Maladies Infectieuses et Tropicales, Université Pierre et Marie Curie, Hôpital Tenon (AP-HP), 4 rue de la Chine, 75020 Paris, France. philippe.bonnard@tnn.ap-hop-paris.fr

Transactions of the Royal Society of Tropical Medicine and Hygiene

|November 20, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Acute Hepatitis B among PWH Switched to Long-Acting Cabotegravir/Rilpivirine: The Context Matters.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026

Same author

Antimicrobial-Resistant Neisseria gonorrhoeae Infections in Men Using Doxycycline Postexposure Prophylaxis: A Substudy of the ANRS 174 DOXYVAC Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2025

Same author

Impact on weight of a Doravirine switch in people living with HIV.

HIV medicine·2025

Same author

The impact of the COVID-19 and mpox outbreaks on behaviours associated with HCV infection among MSM: results from the prerandomisation phase of a clinical trial.

AIDS (London, England)·2025

Same author

Correction to "Impact of vaccination with third generation modified vaccinia Ankara and sexual behaviour on mpox incidence in men who have sex with men: analysis among participants of the ANRS-174 DOXYVAC trial" [The Lancet Regional Health-Europe 45, October 2024, 101020].

The Lancet regional health. Europe·2025

Same author

[Sexual transmission of strongyloidiasis in men who have sex with men (MSM) in Paris].

Medecine tropicale et sante internationale·2025

Splenic infarction is a rare complication of malaria, even during effective treatment. Clinicians should consider this possibility in patients experiencing left hypochondrial pain during malaria therapy.

Area of Science:

Tropical Medicine
Infectious Diseases
Hematology

Background:

Malaria is a significant cause of fever in travelers returning from tropical regions, with Plasmodium falciparum being the predominant species.
Approximately 7000 malaria cases are reported annually in France, highlighting the importance of vigilance in returning travelers.

Observation:

A case of splenic infarction during effective antimalarial treatment for uncomplicated acute malaria is presented.
Seven additional cases of splenic infarction complicating malaria treatment were identified in the literature.

Findings:

Splenic infarction can occur despite appropriate antimalarial prophylaxis and treatment.
Unlike previously reported cases, splenic infarction occurred early in the described patient, who was older than the other seven patients.

Related Experiment Videos

Clinical outcomes for all reported cases, including the presented one, were favorable.

Implications:

Clinicians should be aware of splenic infarction as a rare complication of malaria treatment.
Left hypochondrial pain during malaria treatment warrants consideration for splenic infarction.
There are currently no known predictive signs for this rare complication.