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Updated: Aug 20, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
Published on: July 11, 2025
Lessons learned from malaria: Italy's past and sub-Sahara's future
Louis F Amorosa1, Gilberto Corbellini, Mario Coluzzi
1School of Medicine, University of Pittsburgh, 120 Ruskin Ave, #214, Pittsburgh, PA 15213, USA. loa3@pitt.edu
Abstract:
No longer a major public health concern in developed countries, malaria kills 1-3 million people annually, mostly children under the age of five in sub-Saharan Africa. In 1998, the WHO launched the Roll Back Malaria (RBM) drive to halve malaria mortality by 2010. This article contrasts the problems confronting RBM with the successful Italian drive to eradicate malaria between the late 19th and mid 20th centuries. The Italians employed education and applied socio-political will; however, ecological and socio-economic conditions in sub-Saharan Africa are more hospitable to the disease. RBM strategies should consider the Italian experience while awaiting a major scientific breakthrough necessary to achieve success.
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