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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
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Published on: February 1, 2022

[Ischemic left ventricular free wall rupture followed by ventricular septal perforation]

Takashi Matsushita1, K Ebisawa, H Konishi

  • 1Division of Cardiovascular Surgery, Jichi Medical School, Tochigi, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|November 24, 2004
PubMed

Insights

A rare case of ischemic ventricular double rupture occurred after coronary angiography. Prompt diagnosis and surgical repair, including fibrin glue and infarction exclusion, led to a successful outcome.

Area of Science:

  • Cardiology
  • Cardiac Surgery

Background:

  • Coronary angiography can precipitate rare but severe cardiac complications.
  • Acute myocardial infarction can lead to ventricular rupture, a life-threatening event.

Observation:

  • A 78-year-old woman presented with chest pain and circulatory collapse post-coronary angiography.
  • Computed tomography revealed pericardial effusion, and surgery identified an oozing lesion on the left ventricular anterior wall.
  • Post-operative deterioration led to the diagnosis of ventricular septal perforation via echocardiography.

Findings:

  • The initial oozing lesion was controlled with fibrin glue sheets under extracorporeal membrane oxygenation.
  • Ventricular septal perforation occurred on the apical anterior wall, necessitating reoperation.
  • Repair using an infarction exclusion method resulted in an uneventful postoperative course.

Implications:

  • Ischemic ventricular double rupture is an exceptionally rare complication of myocardial infarction.
  • Intensive follow-up is crucial for patients with cardiac rupture risk factors.
  • Early recognition and surgical intervention are key to managing ventricular rupture.

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