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Cartilage restoration: overview of treatment options

Jason M Scopp1, Bert R Mandelbaum

  • 1Peninsula Orthopaedic Associates, Salisbury, Md, USA.

The Journal of Knee Surgery
|November 24, 2004
PubMed
Abstract

No abstract available in PubMed .

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

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