Related Experiment Video
Updated: Aug 17, 2026

A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
Published on: February 14, 2021
[Pathological development of researches on intervertebral disc degeneration]
1Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Abstract:
This article reviews the literature about the etiology and pathology of intervertebral disc degeneration. The degeneration of intervertebral disc is associated with certain biomechanical factor. Stress can directly lead to the rupture of intervertebral disc and, more importantly, change its biological properties. And then, it can trigger the process of degeneration via inflammatory mechanism which may include autoimmunity.
More Related Videos
Related Concept Videos
Spinal Cord Injury ll: Pathophysiology
Herniated Intervertebral Disc l: Introduction
Degenerative Disc Disease I: Introduction
Degenerative Disc Disease ll: Pathophysiology

