Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional implications of the pulmonary microcirculation. An update.

W G Guntheroth1, D L Luchtel, I Kawabori

  • 1Department of Pediatrics, University of Washington, Seattle 98195.

Chest
|April 1, 1992
PubMed
Summary

The pulmonary microcirculation resembles systemic circulation, featuring tubular capillaries on the alveolar wall. The study found no support for the sheet-and-post model in pulmonary capillary anatomy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Infarction patterns in endocardial fibroelastosis.

Circulation·2015
Same author

Sensitivity and specificity of echocardiographic evidence of tamponade: implications for ventricular interdependence and pulsus paradoxus.

Pediatric cardiology·2007
Same author

Characterization of bronchial-to-pulmonary communications.

Archives of physiology and biochemistry·2005
Same author

Thermal stress in sudden infant death: Is there an ambiguity with the rebreathing hypothesis?

Pediatrics·2001
Same author

Effects of ozone exposure on nuclear factor-kappaB activation and tumor necrosis factor-alpha expression in human nasal epithelial cells.

Toxicological sciences : an official journal of the Society of Toxicology·2001
Same author

Large ductal flow may cause high velocity in the descending aorta without coarctation: improved diagnosis using the continuity equation.

The American journal of cardiology·2001

Area of Science:

  • Pulmonary Physiology
  • Microcirculation Anatomy
  • Respiratory System Biology

Background:

  • Two models, sheet-and-post and tubular, exist for pulmonary microcirculation anatomy.
  • Understanding pulmonary microcirculation is crucial for respiratory function.
  • Previous models lacked definitive morphologic evidence.

Purpose of the Study:

  • To review and compare evidence for the sheet-and-post and tubular paradigms of pulmonary microcirculation.
  • To analyze functional implications of each model on blood flow, recruitment, distension, and diffusion.
  • To determine the most accurate model for pulmonary capillary structure.

Main Methods:

  • Review of existing literature on pulmonary microcirculation anatomy.
  • Comparative analysis of morphologic evidence for competing models.

Related Experiment Videos

  • Evaluation of functional consequences based on proposed structures.

    • Main Results:

    • The pulmonary microcirculation's structure is fundamentally similar to systemic microcirculation.
    • Evidence supports a structure with two layers of tubular capillaries on the alveolar wall.
    • No morphologic or theoretical advantages were found for the sheet-and-post concept.

    Conclusions:

    • The tubular paradigm accurately describes pulmonary microcirculation.
    • The pulmonary microcirculation is not uniquely structured compared to systemic circulation.
    • The sheet-and-post model is not supported by current morphologic or theoretical evidence.