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Updated: Aug 20, 2026

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
[Alkylphenols in the environment: a risk for human health?]
F Ensabella1, F Materazzo, T Severi
1Dipartimento di Scienze di Sanità Pubblica G. Sanarelli, Università degli Studi di Roma La Sapienza.
Abstract:
Endocrine Disrupting Chemicals (ECD) are a class of chemical compounds widely utilized for many industrial and civil applications and, consequently, widely diffused in the environment. Due to their chemical-physical characteristics, ECD may interfere with several endocrine functions in humans. Alkylphenols (APs), mainly produced by biodegradation of alkylphenols polyethoxylates surfactants, are a relevant group of ECD, both for their environmental diffusion and demonstrated estrogenic activity. Aim of this paper is to assess the potential risk of exposure to APs for humans, on the basis of the available data in literature concerning APs: environmental levels, accumulation in sediments and biota, toxicological effects on experimental animals.
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