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Updated: Jul 31, 2026

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
Published on: February 21, 2011
[Quantitative spectral evaluation of vocal hypofunction]
F Núñez Batalla1, P Corte Santos, B Señaris González
1Servicio de Otorrinolaringología, Hospital Universitario Central de Asturias, Oviedo. fnunezb@seorl.net
Abstract:
The purpose of this study was to explore the interaction between voice asthenicity and the acoustic prediction of vocal hypofunction. One hundred and seven phonatory samples of Reinke's edema were categorized by listeners using GRBAS scale. Seven frequency and time domain parameters were used to predict perceptual severity of asthenicity. Logistic regresion analysis showed that a useful measure for the prediction of asthenicity was the loss of harmonic components in the middle and upper portion of the spectrum. A spectral classification of vocal hypofunction is proposed.
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