Related Experiment Video
Updated: Aug 20, 2026

Single Cell Collection of Trophoblast Cells in Peri-implantation Stage Human Embryos
Published on: June 12, 2020
An ontological view of the human embryo. A paradigm
1Centro de Biologia Molecular, CSIC-UAM, Facultad de Ciencias, Canto Blanco, 28049 Madrid, Spain. Calonso@cbm.uam.es
Abstract:
In the present paper I analyze the existing paradigms explaining the ontological status of the organisms originating during a given developmental process and the potentiality these paradigms offer. These paradigms give us a hint of the ontological and ethical status of these organisms. It is described that during the history of human thought two theories have been developed to explain the origin of living organisms. One theory placed the world's origin and the origin of living organisms in a transcendent reality while the second stated that the growing complexity of these organisms was rooted in an internal 'dynamis' (the internal potential of a thing, generally a living thing, to acquire new properties) that is present in each one of them. These paradigms are analysed concluding that at the time they were formulated there was no formal understanding of the process of development because the emergence of novelties through evolution was not included in them. At that time growth and development were two aspects of the same thing. A critical turning point in biological and philosophical thinking was provided by the founders of the DNA paradigm as the program directing development. Due to new insights, a paradigm is presented here which includes the epigenesic information as an essential element of the program of development together with the DNA. The consequence of this paradigm is that the program of development is time- and space-dependent and that the biological elements which originate during the process are not preformed but adopt specific values. This way of thinking introduces new approaches to the analysis of the value of the human embryo with repercussions in the ethical discussions on research programs using embryonic stem cells.
Related Concept Videos
Functions of Life
Metabolism
The basic function of an organism is to consume energy and molecules in foods, convert some of it into fuel for movement, sustain body functions, and build and maintain body structures. There are two types of reactions that accomplish this: anabolism and catabolism.
Anabolism is the process whereby...
Development of the Sexual Organs in the Embryo and Fetus
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...
Cleavage and Blastulation
Gastrulation
Zygotic Development And Stem Cell Formation
Fertilization

