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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Resistance development in community-acquired strains of methicillin-resistant Staphylococcus aureus: an in vitro
Wendy J Munckhof1, Sharon L Kleinschmidt, John D Turnidge
1Infection Management Services, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Qld. 4102, Australia. wendy_munckhof@health.qld.gov.au
Abstract:
This study compares in vitro antimicrobial resistance development between strains of Staphylococcus aureus including newly described community-acquired methicillin-resistant strains (CA-MRSA). High-level resistance developed in all strains of S. aureus after exposure to rifampicin and gentamicin and in some strains after fusidic acid exposure, independent of methicillin resistance phenotype. Resistance did not develop after exposure to clindamycin, cotrimoxazole, ciprofloxacin, linezolid, or vancomycin. These results have important implications for therapy of CA-MRSA infections.
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